Materials include an original letter from John K. Kane to Thomas L. Kane updating him on the new political situations and issues in the United States, specifically Philadelphia. He mentions the new cabinet, banking system, and politicians in charge of the state. Dated December 5, 1840.

Materials include an original letter from John K. Kane and Jane Duval Leiper Kane to their son Thomas L. Kane informing the latter that he is sending a packet of information including President William Henry Harrison's message. They also tell Thomas that the banks have not announced their intention to resume business. Dated December 19, 1840.

Materials include an original letter from John K. Kane to Thomas L. Kane complaining that Thomas has not mentioned his health in his letters. He asks about plans for Thomas's return home from England. Dated January 24, 1841.

Materials include an original letter from John K. Kane and Uncle Bill (William Leiper) to Thomas L. Kane. The letter is badly damaged with text missing, but it contains a request for Thomas to return home since the family misses him and mentions Thomas's birthday, which was on January 27th. It also describes Pennsylvania Governor David R. Porter's visit to the Kane household. Dated January 29, 1841.

Materials include an original letter from John K. Kane and Jane Duval Leiper Kane to Thomas L. Kane that lists more problems with the banks and the members of the new cabinet. Dated February 16, 1841.

Materials include an original letter from John K. Kane to his son Elisha Kent Kane. It says that the acting Secretary of the Navy sent word that Elisha is to be on the next list of appointments and will be commissioned into the Navy. It also includes an update about the Kane family. Dated May 31, 1843.

Materials include an original letter from John K. Kane and Thomas L. Kane to Elisha Kent Kane with information about Elisha's commission, the family, and current events. John says that Delaware County is suffering from severe damage caused by several heavy rainstorms and floods. Dated August 12-14, 1843.

Materials include an original letter from John K. Kane and Thomas L. Kane to Elisha Kent Kane with advice to visit Manila, Philippines. They tell him that his mother's (Jane Duval Leiper Kane) health has improved. Thomas gives Elisha a description of their mother's and their siblings' well-being. Dated September 27, 1843.

Materials include an original letter from John K. Kane to Elisha Kent Kane. John shares his feelings of loneliness with Elisha, tells him that he is trying to secure letters for Elisha's brother Thomas L. Kane in France, and describes the presidential race between James C. Calhoun and Martin Van Buren. Dated September 28-30, 1843.

Materials include an original letter from John K. Kane to Elisha Kent Kane telling him about the problems at the Pennsylvania Medical College and asking for Elisha to write him at every opportunity. Dated October 12, 1843.