Contains drafts of biographies and a novel, as well as notes and other materials written by Kane. Materials focus on Thomas L. Kane and distant branches of the family, including the Van Rensselaer and Hawthorne families. Items date from between 1856 and 1881.

Contains Kane's manuscripts, including her fourteen diaries, beginning in 1853 and ending in 1909, although there are numerous gaps in their coverage. The first nine date before her husband's death, and include accounts of his life. Also includes the papers of her father, William Wood, as well as Kane's mostly unpublished work.

Contains autobiographical and literary writings by Elizabeth Wood Kane. Most of the documents, including travel accounts, focus on her life and experiences. She writes about her husband Thomas L. Kane serving in the Civil War, her experiences with the Mormons in the West, and Also includes family history projects, getting to meet President Ulysses S. Grant, and other family affairs. Materials also include family history writings like the autobiography of her father. Dated 1856-1921.

Contains a manuscript relating Kane's experiences while travelling with her son Evan O'Neill Kane to the State Medical Societies to the Pan-American Congress in 1896. Includes copies of correspondence and published articles. Materials date from between 1896 and 1897.

Materials include a manuscript written by Elizabeth Wood Kane describing Ulysses S. Grant's visit with the Kane family; there are details about their activities, discussions, and her impressions of the presidential party. Many of their conversations were about politics, religion, and race relations. Dated 1869.

Contains letters, notes, clippings, and other materials relating to Kane's visit to Utah in 1872. Includes information on their travels, conditions in Utah, and the publication of her account in the book Twelve Mormon Homes. Materials date from between 1860 and 1877.

Contains manuscripts, drafts, and source materials related to Kane's history of Kane, Pennsylvania. Includes information on the Kane family's role in settlement and autobiographical writings. Materials date from between approximately 1866 and 1896.

Contains digital images of photographs and letters related to several families in the Escalante, Utah, area. Digitized on May 23-24, 2014.

Contains correspondence, a journal, and published articles by Kane. Most of the unpublished materials deal with the Kane family and his personal interests, while the articles relate to his medical practice. Materials date from between 1872 and 1930.

Contains digital images of photographs related to the Griffin family. Digitized in Escalante, Utah, on May 24, 2014.