Contains a letter, several notes, picture cards, and a botanical pressing found within printed works in the Kane family collection. The letter is concerns a trial and injustice in the life of Thomas L. Kane and is signed by his aunt. The notes include copied scriptural and lyrical passages, as well as notes on a book concerning genealogy. The picture cards depict religious scenes. Materials date from 1849 to the late 19th century.

Contains correspondence between Kane and his wife Elizabeth during his service in the Civil War. Includes information on the course of the war, the Kane family, and personal business. Materials date from between 1861 and 1863.

Contains correspondence between Kane and family members and friends. Includes discussion of the conduct of the war, command of the Bucktails Regiment, and family and personal news. Also includes correspondence on Kane's resignation in 1863, and later reminiscences. Materials date from between 1861 and 1877.

Contains correspondence, notes, clippings, and other material related to Kane's wartime service. Also contains additional materials related to the war without clear ties to Kane. Materials date from between 1861 and 1883.

Contains material relating to Kane's Civil War experience, including his correspondence with his wife, his capture by the Confederate Army, his release in a prisoner exchange, his Bucktails regiment, and a variety of post-war materials, including his correspondence with the artist of the murals for the Battle of Gettysburg.