Contains correspondence, bills, receipts, statements, ledgers, and other material relating to the Kane family's business activities. Includes information on the Kane Plumbing Company, Kane Gas Light & Heating, Kane Summit Hospital, and Kushequa Brick Company, as well as other enterprises. Materials date from between 1886 and 1943.

Contains correspondence, clippings, maps, and financial records relating to core family business activities, including the development of western Pennsylvania, the history of town of Kane, railroad investments, and other businesses. Materials date from between 1844 and 1943.

Contains correspondence, notes, daybooks, and other materials relating to the Kane family's involvement in railroad development in McKean County, including the Philadelphia and Erie Railroad, the Kinzua Viaduct Railroad, the New York and Erie Railroad, and the Pennsylvania Railroad Company. Materials date from between 1856 and 1932.

Contains correspondence, maps, notes, financial records, clippings, and other materials relating to the McKean and Elk Land and Improvement Company. Includes information on Thomas L. Kane's work as an agent for the company, progress being made in developing the region, financial concerns of the company, and legal actions surrounding the property. Materials date from between 1844 and 1926.

Contains correspondence, insurance policies, and other documents related to Kane's business dealings. Includes information on land sales, his service on various boards, and other matters. Materials date from between 1846 and 1884.