Contains materials related to the life and activites of Elizabeth Wood Kane. It is composed primarily of a series of journals, several bound books, and a wide variety of papers and newspaper clippings. Subjects include records of daily life, domestic tasks, family matters, the settlement of Kane, Pennsylvania, and Elizabeth's activities as a medical doctor. Materials date between 1868 and 1907.

Contains a soft-bound recipe book belonging to Kane, and various newspaper clippings and notes found within it. The recipe book contains not only recipes, but also instructions detailing how to perform other domestic tasks like crocheting. The newspaper clippings and notes are mostly recipes, but also include articles and advertisements concerning domestic subjects. All materials are undated.

Contains correspondence, bills, receipts, statements, ledgers, and other material relating to the Kane family's business activities. Includes information on the Kane Plumbing Company, Kane Gas Light & Heating, Kane Summit Hospital, and Kushequa Brick Company, as well as other enterprises. Materials date from between 1886 and 1943.

Contains correspondence, clippings, maps, and financial records relating to core family business activities, including the development of western Pennsylvania, the history of town of Kane, railroad investments, and other businesses. Materials date from between 1844 and 1943.

Contains correspondence, notes, daybooks, and other materials relating to the Kane family's involvement in railroad development in McKean County, including the Philadelphia and Erie Railroad, the Kinzua Viaduct Railroad, the New York and Erie Railroad, and the Pennsylvania Railroad Company. Materials date from between 1856 and 1932.

Contains correspondence, insurance policies, and other documents related to Kane's business dealings. Includes information on land sales, his service on various boards, and other matters. Materials date from between 1846 and 1884.