Contains correspondence, bills, receipts, statements, ledgers, and other material relating to the Kane family's business activities. Includes information on the Kane Plumbing Company, Kane Gas Light & Heating, Kane Summit Hospital, and Kushequa Brick Company, as well as other enterprises. Materials date from between 1886 and 1943.

Contains correspondence, clippings, maps, and financial records relating to core family business activities, including the development of western Pennsylvania, the history of town of Kane, railroad investments, and other businesses. Materials date from between 1844 and 1943.

Contains correspondence, insurance policies, and other documents related to Kane's business dealings. Includes information on land sales, his service on various boards, and other matters. Materials date from between 1846 and 1884.