Contains biology lectures and laboratory records from Talmage's time as a science educator at Brigham Young Academy. Dated approximately 1884 to 1889.

Contains biological observations, biology sketchbooks, and laboratory notebooks made or initiated by James E. Talmage during his time as President of the Latter-day Saints' College in Salt Lake City, Utah. Dated approximately 1889 to 1900.

Contains lectures, student papers, and other materials from James E. Talmage's time as both president and professor at the University of Utah. These date from 1893 to 1911.

Contains pamphlets, magazine and newspaper articles, and printed advertisements collected by James E. Talmage. Most of these publications deal with geology and volcanology. Some are authored or partially authored by Talmage. Materials date from 1883 to 1910.

Contains materials relating to scientific and professional societies and Talmage's career as consulting geologist and mining engineer, dated 1882 to 1926. Includes material from the Royal Society of Edinburgh, Salt Lake Literary and Scientific Association, Royal Microscopical Society, Utah Microscopical Society, Geological Society of London, and Geological Society of America.

Includes family material (ordination certificates, mission farewell programs, receipts, genealogical records, funeral programs, poetry and short stories, etc.) and memorabilia.

Contains addresses and ads for them, published manuscripts on doctrinal topics (including those for Jesus the Christ and Articles of Faith; material on loose topics is alphabetical), notebooks, newspaper articles (by Talmage and others, syndicated and otherwise), and correspondence; also includes a collection of syndicated articles, filed alphabetically by newspaper.

Contains the journals, pocket diaries, and a personal account book kept by James E. Talmage from December 1879 to July 4, 1933. These diaries cover his life from his time as a student at Brigham Young Academy, through his graduate school and academic career, and finally to his time spent as a member of Quorum of the Twelve Apostles in the Church of Jesus Christ of Latter-day Saints.

Contains lecture notes and published reports of lectures given by James E. Talmage, from 1886 to 1912, as well as an program for a baccalaureate address at Weber College on May 20, 1928. Most of the lectures are on various scientific and historical topics.