Contains an autobiography, portrait, and will by Kane, providing a biographical summary of his life and activities. Materials date from between 1849 and 1857.

Contains certificates, letters of correspondence, and other materials. Materials date between 1828 to 1854.

Contains letters of correspondence between Kane and various national and local political leaders. Letters were recieved by Kane while he was living in Philadelphia, Pennsylvania between 1832 and 1856.

Contains outgoing and some incoming correspondence by Kane. Letters are primarily addressed to family members, and include information about family activities, politics, travel, and other subjects. Materials date from between 1809 and 1854.

Contains correspondence, biographical materials, and other documents related to early Kane family and business activities, as well as the papers of the Kane. Includes both personal papers and materials relating to his work as a judge and political figure. Materials date from between 1773 and 1916.

Contains genealogical information, biographies, correspondence, receipts, and other materials related to Kane's ancestors and other members of the extended Kane family. Items document personal activities, family relations, business ventures and transactions, and other topics. Materials date from between 1773 and 1916.

Contains letters, the majority of which are sent to John K. Kane in Philadelphia, Pennsylvania; legal documents, including those dealing with Dr. Robert Patterson's bond and mortgage, the Julia Taylor estate, and Girard Bank; and promissory notes, protests of promissory notes, and protests of non-payment of promissory notes. Materials date from between 1817 and 1851.

Contains photographs found in the second volume of the Kane family photograph album which were not mounted. The photographs primarily depict people and portraits of people known to the Kane family. These include Thomas L. Kane's father, John K. Kane, and many unnamed people who are presumably Kane or Wood family members. A single photograph depicts a living room. Materials are largely undated and unlabeled, but presumably date from the mid 19th century to early 20th century.

Handwritten and signed letter dated February 1, 1846 and addressed to "dear Sir." Kane writes that he has recently been visited by a "Mr. Benson and Mr. Little" of the Mormon Church. They asked Kane's opinion of a case relating to a Joseph Sidwell. Kane comments on the Mormon plans to emigrate to the West U.S. "I am thoroughly convinced of the general integrity and right mindedness of this persecuted sect."